2-(4-甲氧基苯基)乙胺盐酸盐合成路线 (共 5 条)
反应条件
1: With caesium carbonate in tert-butyl methyl ether; N,N-dimethyl-formamide T=40°C; 11 h; Inert atmosphere; 2: With hydrogenchloride in isopropanol acetate; water; ethyl acetate 0.5 h;
参考文献
Magnus, Nicholas A.; Astleford, Bret A.; Brennan, John; Stout, James R.; Tharp-Taylor, Roger W.
Organic Process Research and Development, 2009 , vol. 13, # 2 p. 280 - 284
反应条件
1: With tri-ruthenium(0)dodecacarbonyl; (HSiMe2)2NH in toluene T=20 - 70°C; 24.17 h; Inert atmosphere; 2: With hydrogenchloride in 1,4-dioxane; ethyl acetate; toluene T=20°C; 0.5 h;
参考文献
Reeves, Jonathan T.; Tan, Zhulin; Marsini, Maurice A.; Han, Zhengxu S.; Xu, Yibo; Reeves, Diana C.; Lee, Heewon; Lu, Bruce Z.; Senanayake, Chris H.
Advanced Synthesis and Catalysis, 2013 , vol. 355, # 1 p. 47 - 52
反应条件
ammonia in methanol T=130°C; 2.5 h; microwave irradiation;
参考文献
Tetrahedron Letters, , vol. 45, # 2 p. 397 - 399
反应条件
hydrogenchloride; hydrogen; palladium on activated charcoal 1) EtOH, H2O, HOAc, 50 deg C, 50 psi, 4h, 2) EtOH; Yield given. Multistep reaction;
参考文献
Journal of Organic Chemistry, , vol. 58, # 12 p. 3299 - 3303
参考文献
Buck
Journal of the American Chemical Society, 1934 , vol. 56, p. 1607
Full Text View citing articles Show Details
Jansen
Recueil des Travaux Chimiques des Pays-Bas, 1931 , vol. 50, p. 617,621