(S)-(+)-3-(2,2-二甲基-1,3-二氧戊环-4-基)-反式-丙酸乙酯合成路线 （共 24 条）
反应条件
1: NaIO4; NaHCO3 / H2O / 1 h / 20 °C 2: 20.0 g / K2CO3 / H2O / 20 h / 20 °C View Scheme
参考文献
Journal of Organic Chemistry, , vol. 70, # 16 p. 6321 - 6329
反应条件
1: DMSO; oxalyl chloride; Et3N / CH2Cl2 / -78 - 20 °C 2: CH2Cl2 / 20 °C View Scheme
参考文献
Journal of the American Chemical Society, , vol. 126, # 42 p. 13600 - 13601
反应条件
toluene-4-sulfonic acid in benzene 12 h; Heating;
参考文献
Chilmonczyk, Zdzislaw; Egli, Markus; Behringer, Christoph; Dreiding, Andre S.
Helvetica Chimica Acta, 1989 , vol. 72, p. 1095 - 1106
反应条件
sulfuric acid in methanol 0.5 h; Ambient temperature;
参考文献
Haefele, Brigitte; Jaeger, Volker
Liebigs Annalen der Chemie, 1987 , p. 85 - 88
反应条件
manganese(IV) oxide in toluene Oxidation; Wittig reaction; 20 h; Heating; Title compound not separated from byproducts;
参考文献
Chemical Communications, , # 14 p. 1337 - 1338
反应条件
1: ethyl bromoacetate With tributylphosphine in tetrahydrofuran T=0°C; Wittig reaction; 0.0833333 h; 2: (R)-(+)-2,2-dimethyl-1,3-dioxolane-4-carboxaldehyde With tetrabutyl ammonium fluoride in tetrahydrofuran T=20°C; Wittig reaction; 3 h; optical yield given as percent dediastereoselective reaction;
参考文献
Synthetic Communications, , vol. 39, # 12 p. 2178 - 2195
反应条件
sodium periodate; sodium hydrogencarbonate; potassium carbonate 1) 1 h; 2) r.t., 24 h; Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Tetrahedron, , vol. 45, # 2 p. 391 - 402
反应条件
sodium periodate; sodium hydrogencarbonate; potassium carbonate 1.) H2O, r.t., 1 h, 2.) 0 deg C - r.t., overnight; Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Journal of Organic Chemistry, , vol. 58, # 23 p. 6292 - 6302
反应条件
lead(IV) acetate; sodium hydrogencarbonate 1.) toluene, 4 h, 2.) 18 h; Yield given. Multistep reaction;
参考文献
Synthetic Communications, , vol. 19, # 20 p. 3529 - 3534
反应条件
1: hydrogen / Pd(OH)2/C / methanol / 2 h 2: 15.6 g / LAH / diethyl ether / 1 h / 0 °C View Scheme
参考文献
Kang, Eun Joo; Cho, Eun Jin; Ji, Mi Kyung; Lee, Young Eun; Shin, Dong Mok; Choi, Soo Young; Chung, Young Keun; Kim, Jong-Seo; Kim, Hie-Joon; Lee, Sueg-Geun; Lah, Myoung Soo; Lee, Eun
Journal of Organic Chemistry, 2005 , vol. 70, # 16 p. 6321 - 6329
