1-(6’-氨基螺[环丙烷-1,3’-吲哚啉]-1’-基)乙酮合成路线 (共 3 条)
反应条件
hydrogenchloride; Pd-C in methanol; ethanol
参考文献
Vertex Pharmaceuticals Incorported
Patent: US2011/98311 A1, 2011 ;
Title/Abstract Full Text Show Details
Vertex Pharmaceuticals Incorporated
Patent: US2012/309758 A1, 2012 ;
US 20120309758 A1
反应条件
1: NaNO3 / sulfuric acid
2: sodium hydrogencarbonate / dichloromethane
3: hydrogenchloride / Pd-C / methanol; ethanol
View Scheme
参考文献
Vertex Pharmaceuticals Incorported
Patent: US2011/98311 A1, 2011 ;
反应条件
1: sodium hydrogencarbonate / dichloromethane
2: hydrogenchloride / Pd-C / methanol; ethanol
View Scheme
参考文献
Vertex Pharmaceuticals Incorported
Patent: US2011/98311 A1, 2011 ;