1-氟-4-[(4-硝基苯基)乙炔基]苯合成路线 （共 5 条）
反应条件
bis-triphenylphosphine-palladium(II) chloride; tetrabutyl ammonium fluoride
T=80°C; Sonogashira cross-coupling reaction; 1 h;
参考文献
Liang, Yun; Xie, Ye-Xiang; Li, Jin-Heng
Journal of Organic Chemistry, 2006 , vol. 71, # 1 p. 379 - 381
反应条件
1: 65 percent / tetrahydrofuran / 3 h / Ambient temperature
2: 84 percent / POCl3, N,N-diethylaniline / 1 h / 90 °C
3: t-BuOK / tetrahydrofuran / 3 h / Ambient temperature
View Scheme
参考文献
Kondo, Koichi; Fujitani, Takumi; Ohnishi, Noriaki
Journal of Materials Chemistry, 1997 , vol. 7, # 3 p. 429 - 433
反应条件
1: 84 percent / POCl3, N,N-diethylaniline / 1 h / 90 °C
2: t-BuOK / tetrahydrofuran / 3 h / Ambient temperature
View Scheme
参考文献
Kondo, Koichi; Fujitani, Takumi; Ohnishi, Noriaki
Journal of Materials Chemistry, 1997 , vol. 7, # 3 p. 429 - 433
反应条件
sodium hydride in dimethyl sulfoxide
参考文献
Gascoyne,J.M. et al.
Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), 1977 , p. 1051 - 1057
反应条件
potassium tert-butylate in tetrahydrofuran
3 h; Ambient temperature;
参考文献
Kondo, Koichi; Fujitani, Takumi; Ohnishi, Noriaki
Journal of Materials Chemistry, 1997 , vol. 7, # 3 p. 429 - 433
