1-(2-氨基-4-氯苯基)-2-氯乙酮合成路线 （共 3 条）
反应条件
1: With hydrogenchloride; water in ethanol
1 h; Reflux;
2: With sodium hydroxide in ethanol; water
pH=Ca. 9;
参考文献
Cinelli, Maris A.; Morrell, Andrew E.; Dexheimer, Thomas S.; Agama, Keli; Agrawal, Surbhi; Pommier, Yves; Cushman, Mark
Bioorganic and Medicinal Chemistry, 2010 , vol. 18, # 15 p. 5535 - 5552
反应条件
aluminium trichloride; boron trichloride in dichloromethane
Heating;
参考文献
Miao, Zhenyuan; Sheng, Chunquan; Zhang, Wannian; Ji, Haitao; Zhang, Jing; Shao, Luecheng; You, Liang; Zhang, Min; Yao, Jianzhong; Che, Xiaoyin
Bioorganic and Medicinal Chemistry, 2008 , vol. 16, # 3 p. 1493 - 1510
反应条件
AlCl3, aluminium chloride; BCl3*Me2S in 1,2-dichloro-ethane
Friedel-Crafts acylation;
参考文献
Cinelli, Maris A.; Morrell, Andrew E.; Dexheimer, Thomas S.; Agama, Keli; Agrawal, Surbhi; Pommier, Yves; Cushman, Mark
Bioorganic and Medicinal Chemistry, 2010 , vol. 18, # 15 p. 5535 - 5552
