1-苄基-1,7-二氮杂螺[4.4]壬烷-7-羧酸叔丁酯合成路线 (共 2 条)
反应条件
triethylamine in dichloromethane
T=20°C; Stirring overnight;
参考文献
TARGACEPT, INC.
Patent: WO2006/23630 A2, 2006 ;
Location in patent: Page/Page column 57-58 ;
反应条件
hydrogen; palladium 10 on activated carbon in methanol
P=2585.81 Torr; 8 h; Parr hydrogenation apparatus;
参考文献
TARGACEPT, INC.
Patent: WO2006/23630 A2, 2006 ;
Location in patent: Page/Page column 58 ;