1: 6-chloro-nicotinic acid With 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; 1-hydroxy-7-aza-benzotriazole in DMF (N,N-dimethyl-formamide) 0.25 h; 2: pyrrolidine With N-ethyl-N,N-diisopropylamine in DMF (N,N-dimethyl-formamide) T=20°C;

1,1'-carbonyldiimidazole in dichloromethane 2 h;

in dichloromethane T=20°C; 24 h;