4-(N-乙酰基)哌啶基2-(5-甲氧基)苯酚甲酮合成路线 （共 5 条）
反应条件
1: SOCl2 / 1,2-dichloro-ethane / 40 - 65 °C
2: AlCl3 / 2 h / Heating
View Scheme
参考文献
Strupczewski, Joseph T.; Allen, Richard C.; Gardner, Beth Ann; Schmid, Blaine L.; Stache, Ulrich; et al.
Journal of Medicinal Chemistry, 1985 , vol. 28, # 6 p. 761 - 769
反应条件
aluminium trichloride
2 h; Heating;
参考文献
Strupczewski, Joseph T.; Allen, Richard C.; Gardner, Beth Ann; Schmid, Blaine L.; Stache, Ulrich; et al.
Journal of Medicinal Chemistry, 1985 , vol. 28, # 6 p. 761 - 769
反应条件
hydrogenchloride
6 h; Heating;
参考文献
Strupczewski, Joseph T.; Allen, Richard C.; Gardner, Beth Ann; Schmid, Blaine L.; Stache, Ulrich; et al.
Journal of Medicinal Chemistry, 1985 , vol. 28, # 6 p. 761 - 769
反应条件
1: 68 percent / 6 N aq. HCl / 6 h / Heating
2: 76 percent / NaHCO3 / CH2Cl2 / 1.5 h / Ambient temperature
View Scheme
参考文献
Strupczewski, Joseph T.; Allen, Richard C.; Gardner, Beth Ann; Schmid, Blaine L.; Stache, Ulrich; et al.
Journal of Medicinal Chemistry, 1985 , vol. 28, # 6 p. 761 - 769
参考文献
American Hoechst Corporation
Patent: US4046900 A1, 1977 ;
