(S)-(+)-α-(甲氧基甲基)苯乙胺 盐酸盐合成路线 （共 6 条）
反应条件
1: thiophenol / dichloromethane; N,N-dimethyl-formamide / 0.75 h / 20 °C
2: hydrogenchloride / water; isopropyl alcohol
View Scheme
参考文献
Stanetty, Christian; Blaukopf, Markus K.; Lachmann, Bodo; Noe, Christian R.
European Journal of Organic Chemistry, 2011 , # 17 p. 3126 - 3130
反应条件
1: pyridine; dichloromethane / 0 - 20 °C
2: potassium hydroxide / water
3: 7 h / 65 °C
4: thiophenol / dichloromethane; N,N-dimethyl-formamide / 0.75 h / 20 °C
5: hydrogenchloride / water; isopropyl alcohol
View Scheme
参考文献
Stanetty, Christian; Blaukopf, Markus K.; Lachmann, Bodo; Noe, Christian R.
European Journal of Organic Chemistry, 2011 , # 17 p. 3126 - 3130
反应条件
1: 7 h / 65 °C
2: thiophenol / dichloromethane; N,N-dimethyl-formamide / 0.75 h / 20 °C
3: hydrogenchloride / water; isopropyl alcohol
View Scheme
参考文献
Stanetty, Christian; Blaukopf, Markus K.; Lachmann, Bodo; Noe, Christian R.
European Journal of Organic Chemistry, 2011 , # 17 p. 3126 - 3130
反应条件
1: sodium carbonate / tetrahydrofuran / 4 h / 0 °C
2: pyridine; dichloromethane / 0 - 20 °C
3: potassium hydroxide / water
4: 7 h / 65 °C
5: thiophenol / dichloromethane; N,N-dimethyl-formamide / 0.75 h / 20 °C
6: hydrogenchloride / water; isopropyl alcohol
View Scheme
参考文献
Stanetty, Christian; Blaukopf, Markus K.; Lachmann, Bodo; Noe, Christian R.
European Journal of Organic Chemistry, 2011 , # 17 p. 3126 - 3130
反应条件
hydrogenchloride in water; isopropyl alcohol
参考文献
Stanetty, Christian; Blaukopf, Markus K.; Lachmann, Bodo; Noe, Christian R.
European Journal of Organic Chemistry, 2011 , # 17 p. 3126 - 3130
反应条件
potassium carbonate in water
参考文献
NEUROCHEM (INTERNATIONAL) LIMITED
Patent: WO2004/113275 A2, 2004 ;
Location in patent: Page 201 ;
