1,4-双(2-吡啶基)哌嗪合成路线 （共 4 条）
参考文献
Louerat, Frederic; Gros, Philippe C.; Fort, Yves
Synlett, 2006 , # 9 p. 1379 - 1383
反应条件
triethylamine in tetrahydrofuran
T=100°C; P=6000480 Torr; 96 h;
参考文献
Matsumoto, Kiyoshi; Fukuyama, Keisuke; Iida, Hirokazu; Toda, Mitsuo; Lown, J. William
Heterocycles, 1995 , vol. 41, # 2 p. 237 - 244
反应条件
1: piperazine With [2,2']bipyridinyl; nickel diacetate; sodium hydride; 1,1-dimethylpropan-1-ol in tetrahydrofuran
T=65°C; 2 h;
2: alpha-chloropyridine With styrene in tetrahydrofuran
T=65°C; 7 h;
参考文献
Brenner, Eric; Schneider, Raphael; Fort, Yves
Tetrahedron, 2002 , vol. 58, # 34 p. 6913 - 6924
参考文献
Hamlin et al.
Journal of the American Chemical Society, 1949 , vol. 71, p. 2731,2732
Show Details
Am. Cyanamid Co.
Patent: US2459367 , 1947 ;
