8-甲氧基-4-氧代-1,4-二氢-1,5-萘啶-3-羧酸乙酯合成路线 (共 6 条)
参考文献
Prana Biotechnology Limited
Patent: WO2004/31161 A1, 2004 ;
Location in patent: Page 95 ;
反应条件
1: sulfuric acid; potassium nitrate / 0 °C / Inert atmosphere
2: methanol / 0 °C / Inert atmosphere
3: hydrogenchloride; iron / methanol; water / Inert atmosphere
4: toluene / Reflux; Inert atmosphere
5: diphenylether / 0.42 h / Reflux; Inert atmosphere
View Scheme
参考文献
Wang, Kun-Yan; Chen, Chen; Liu, Jin-Fang; Wang, Qin; Chang, Jin; Zhu, Hong-Jun; Li, Chong
Organic and Biomolecular Chemistry, 2012 , vol. 10, # 33 p. 6693 - 6704
反应条件
1: methanol / 0 °C / Inert atmosphere
2: hydrogenchloride; iron / methanol; water / Inert atmosphere
3: toluene / Reflux; Inert atmosphere
4: diphenylether / 0.42 h / Reflux; Inert atmosphere
View Scheme
参考文献
Wang, Kun-Yan; Chen, Chen; Liu, Jin-Fang; Wang, Qin; Chang, Jin; Zhu, Hong-Jun; Li, Chong
Organic and Biomolecular Chemistry, 2012 , vol. 10, # 33 p. 6693 - 6704
反应条件
1: hydrogenchloride; iron / methanol; water / Inert atmosphere
2: toluene / Reflux; Inert atmosphere
3: diphenylether / 0.42 h / Reflux; Inert atmosphere
View Scheme
参考文献
Wang, Kun-Yan; Chen, Chen; Liu, Jin-Fang; Wang, Qin; Chang, Jin; Zhu, Hong-Jun; Li, Chong
Organic and Biomolecular Chemistry, 2012 , vol. 10, # 33 p. 6693 - 6704
反应条件
1: toluene / Reflux; Inert atmosphere
2: diphenylether / 0.42 h / Reflux; Inert atmosphere
View Scheme
参考文献
Wang, Kun-Yan; Chen, Chen; Liu, Jin-Fang; Wang, Qin; Chang, Jin; Zhu, Hong-Jun; Li, Chong
Organic and Biomolecular Chemistry, 2012 , vol. 10, # 33 p. 6693 - 6704
反应条件
in diphenylether
0.416667 h; RefluxInert atmosphere;
参考文献
Wang, Kun-Yan; Chen, Chen; Liu, Jin-Fang; Wang, Qin; Chang, Jin; Zhu, Hong-Jun; Li, Chong
Organic and Biomolecular Chemistry, 2012 , vol. 10, # 33 p. 6693 - 6704