3-甲基-5-硝基-1H-吲唑-7-胺合成路线 （共 2 条）
反应条件
1: 94 percent / concd. H2SO4; concd. HNO3 / 3 h / 0 - 20 °C
2: 61 percent / aq. (NH4)2S / ethanol / 80 °C
View Scheme
参考文献
Li, Xiaoming; Chu, Sam; Feher, Victoria A.; Khalili, Mitra; Nie, Zhe; Margosiak, Stephen; Nikulin, Victor; Levin, James; Sprankle, Kelly G.; Tedder, Martina E.; Almassy, Robert; Appelt, Krzysztof; Yager, Kraig M.
Journal of Medicinal Chemistry, 2003 , vol. 46, # 26 p. 5663 - 5673
反应条件
1: 86 percent / hydrazine / dimethylformamide / 16 h / 110 °C
2: 94 percent / concd. H2SO4; concd. HNO3 / 3 h / 0 - 20 °C
3: 61 percent / aq. (NH4)2S / ethanol / 80 °C
View Scheme
参考文献
Li, Xiaoming; Chu, Sam; Feher, Victoria A.; Khalili, Mitra; Nie, Zhe; Margosiak, Stephen; Nikulin, Victor; Levin, James; Sprankle, Kelly G.; Tedder, Martina E.; Almassy, Robert; Appelt, Krzysztof; Yager, Kraig M.
Journal of Medicinal Chemistry, 2003 , vol. 46, # 26 p. 5663 - 5673
