3-乙酰硫基-2-甲基丙酰氯合成路线 (共 3 条)
参考文献
Dainippon Pharmaceutical Co., Ltd.
Patent: US4248883 A1, 1981 ;
反应条件
pyridine; thionyl chloride in toluene
1.5 h; Ambient temperature;
参考文献
Suh, John T.; Skiles, Jerry W.; Williams, Bruce E.; Youssefyeh, Raymond D.; Jones, Howard; et al.
Journal of Medicinal Chemistry, 1985 , vol. 28, # 1 p. 57 - 66
反应条件
1: With potassium hydroxide in water
2: With thionyl chloride
1 h; Reflux;
参考文献
Ismail, Mohamed A.H.; Nabil Aboul-Enein; Abouzid, Khaled A.M.; Abou El Ella, Dalal A.; Ismail, Nasser S.M.
Bioorganic and Medicinal Chemistry, 2009 , vol. 17, # 10 p. 3739 - 3746