反应条件
1: thionyl chloride / 1,2-dichloro-ethane / 4 h / Reflux 2: ammonia / 1,2-dichloro-ethane / 20 °C 3: palladium 10 on activated carbon; hydrogen / methanol 4: sodium hydrogensulfite / N,N-dimethyl acetamide / 3 h / 150 °C 5: thionyl chloride / 1,2-dichloro-ethane; N,N-dimethyl-formamide / 0.5 h / 50 °C View Scheme
参考文献
European Journal of Medicinal Chemistry, , vol. 46, # 7 p. 2709 - 2721