反应条件
1: 1) n-BuLi, triphenylmethane / 1) ether, HMPA, hexane, 0 deg C, 2) ether, 0 deg C, 15 min
2: diethyl ether; hexane; hexamethylphosphoric acid triamide / 3 h / Ambient temperature
3: 1) n-BuLi / 1) THF, HMPA, hexane, -78 deg C, 45 min, 2) THF, -78 deg C to room temperature, overnight
4: 52 percent / Cu(OAc)2*H2O / tetrahydrofuran; H2O / 0.67 h
5: 1) sodium hydride / 1) DMSO, room temperature, 15 min, 2) DMSO, 60 deg C, 3 h
6: p-toluenesulphonic acid / acetone / 5 h
View Scheme
参考文献
Trehan, I. R.; Kad, G. L.; Gupta, Sangita; Verma, Neena; Singh, Labh
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1987 , vol. 26, # 1-12 p. 811 - 813
