1-(1H-1,2,3-苯并噻唑-1-基)乙酮合成路线 （共 10 条）
反应条件
in acetonitrile T=306.5 - 375.4°C; Kinetics;
参考文献
Journal of Physical Organic Chemistry, , vol. 17, # 4 p. 267 - 272
反应条件
iodine; sodium hydrogencarbonate in 1,2-dichloro-ethane
T=80°C; 24 h;
参考文献
Chen, Wenlin; Yan, Rulong; Tang, Dong; Guo, Shuaibo; Meng, Xu; Chen, Baohua
Tetrahedron, 2012 , vol. 68, # 38 p. 7956 - 7959
反应条件
N-ethyl-N,N-diisopropylamine in toluene
T=80 - 95°C; 2.66667 h; Large scale;
参考文献
Shu, Lianhe; Wang, Ping; Radinov, Roumen; Dominique, Romyr; Wright, James; Alabanza, Lady Mae; Dong, Yan
Organic Process Research and Development, 2013 , vol. 17, # 1 p. 114 - 119
反应条件
N-bromosuccinmide; potassium tert-butylate in ethyl acetate
T=60°C; 6 h; Green chemistry;
参考文献
Chen, Wen-Lin; Li, Ji-Hui; Meng, Xu; Tang, Dong; Guo, Shuai-Bo; Chen, Bao-Hua
Tetrahedron Letters, 2013 , vol. 54, # 4 p. 295 - 299
反应条件
in toluene
12 h; Heating;
参考文献
Katritzky, Alan R.; Shcherbakova, Irina V.
Journal of Heterocyclic Chemistry, 1996 , vol. 33, # 6 p. 2031 - 2036
反应条件
in tetrahydrofuran
Condensation; 24 h; Heating;
参考文献
Katritzky; Zhang; Haleem; Hussein; Fang; Steel
Journal of Organic Chemistry, 2001 , vol. 66, # 16 p. 5606 - 5612
反应条件
potassium hydroxide; tetrabutylammomium bromide in water; 1,2-dichloro-ethane
T=20°C; Alkylation; 1.5 h;
参考文献
Samet; Yamskov; Kachala; Semenov
Russian Chemical Bulletin, 1999 , vol. 48, # 3 p. 552 - 556
反应条件
potassium carbonate in acetone
5 h; Heating;
参考文献
Pchelka, Beata K.; Loupy, Andre; Petit, Alain
Tetrahedron Asymmetry, 2006 , vol. 17, # 17 p. 2516 - 2530
反应条件
sodium hydride
1.) acetonitrile, RT, 20 min, 2.) acetonitrile, reflux, 25 h; Yield given. Multistep reaction;
参考文献
Cho, Su-Dong; Chung, Joo-Wha; Kim, Sung-Kyu; Kweon, Deok-Heon; Park, Ki-Hoon; Yoon, Yong-Jin
Journal of Heterocyclic Chemistry, 1996 , vol. 33, # 2 p. 315 - 318
反应条件
sodium hydroxide in ethanol
1 h; Heating;
参考文献
Katritzky, Alan R.; Belyakov, Sergei A.; Henderson, Scott A.; Steel, Peter J.
Journal of Organic Chemistry, 1997 , vol. 62, # 23 p. 8215 - 8217
