1: pyridine-3,5-dicarboxylic acid With caesium carbonate in N,N-dimethyl-formamide 1 h; 2: n-tetradecyl iodide in N,N-dimethyl-formamide T=75°C;

1.1: 98 percent / Et3N / CH2Cl2 / 0.67 h / 0 °C 2.1: 70 percent / NaI / acetone / 2 h / Heating 3.1: Cs2CO3 / dimethylformamide / 1 h 3.2: 88 percent / dimethylformamide / 75 °C View Scheme

1.1: 70 percent / NaI / acetone / 2 h / Heating 2.1: Cs2CO3 / dimethylformamide / 1 h 2.2: 88 percent / dimethylformamide / 75 °C View Scheme