7-硝基-2-苯基-1H-吲哚合成路线 （共 6 条）
反应条件
potassium tert-butylate in 1-methyl-pyrrolidin-2-one
T=60 - 70°C; 7 h;
参考文献
Chiou, Chun-Tang; Chen, Grace Shiahuy; Chen, Meng-Ling; Li, Huoming; Shi, Lei; Huang, Xiang-Hong; Dai, Wei-Ming; Chern, Ji-Wang
ChemMedChem, 2010 , vol. 5, # 9 p. 1489 - 1497
反应条件
copper(l) iodide; tetra-(n-butyl)ammonium iodide; N,N,N',N'-tetramethylguanidine; tetrakis(triphenylphosphine) palladium(0) in N,N-dimethyl-formamide
T=100°C; Sonogashira cross-coupling-heteroannulation; 3.5 h;
参考文献
Sun, Li-Ping; Huang, Xiang-Hong; Dai, Wei-Min
Tetrahedron, 2004 , vol. 60, # 48 p. 10983 - 10992
反应条件
1: 88 percent / NaH / tetrahydrofuran / 24 h / 20 °C
2: 52 percent / CuI; Bu4NI; 1,1,3,3-tetramethylguanidine / Pd(PPh3)4 / dimethylformamide / 3.5 h / 100 °C
View Scheme
参考文献
Sun, Li-Ping; Huang, Xiang-Hong; Dai, Wei-Min
Tetrahedron, 2004 , vol. 60, # 48 p. 10983 - 10992
反应条件
1: 86 percent / pyridine / tetrahydrofuran / 9 h / 20 °C
2: 88 percent / NaH / tetrahydrofuran / 24 h / 20 °C
3: 52 percent / CuI; Bu4NI; 1,1,3,3-tetramethylguanidine / Pd(PPh3)4 / dimethylformamide / 3.5 h / 100 °C
View Scheme
参考文献
Sun, Li-Ping; Huang, Xiang-Hong; Dai, Wei-Min
Tetrahedron, 2004 , vol. 60, # 48 p. 10983 - 10992
反应条件
1: copper(l) iodide; tetrakis(triphenylphosphine) palladium(0); tetra-(n-butyl)ammonium iodide; triethylamine / acetonitrile / 2 h / 20 °C / Inert atmosphere
2: potassium tert-butylate / 1-methyl-pyrrolidin-2-one / 7 h / 60 - 70 °C / Inert atmosphere
View Scheme
参考文献
Chiou, Chun-Tang; Chen, Grace Shiahuy; Chen, Meng-Ling; Li, Huoming; Shi, Lei; Huang, Xiang-Hong; Dai, Wei-Ming; Chern, Ji-Wang
ChemMedChem, 2010 , vol. 5, # 9 p. 1489 - 1497
反应条件
in various solvent(s)
4 h; Heating;
参考文献
Gupta, K. C.; Manglum, P.
Journal of the Indian Chemical Society, 1988 , vol. 65, p. 223 - 225
