2-乙酰基-3-(4-羟基苯基)-丙烯酸合成路线 （共 11 条）
反应条件
hydrogen; lt;Rh((R)-cycphos)(NBD)gt;PF6 in tetrahydrofuran T=25°C; P=760 Torr;
参考文献
Riley, Dennis P.; Shumate, Robert E.
Journal of Organic Chemistry, 1980 , vol. 45, # 25 p. 5187 - 5193
反应条件
1: 79 percent / 3 N HCl / 8 h / 80 °C 2: 78 percent / Zn(Hg), 3 N HCl / toluene / 8 h / 100 °C View Scheme
参考文献
Wong; Xu; Chang; Lee
Synthesis, 1992 , # 8 p. 793 - 797
反应条件
hydrogen; rhodium(I)-(S,S)-skewphos complexes in tetrahydrofuran Ambient temperature; Yield given;
参考文献
MacNeil, Patricia A.; Roberts, Nicholas K.; Bosnich, B.
Journal of the American Chemical Society, 1981 , vol. 103, # 9 p. 2273 - 2280
反应条件
hydrogen; triethylamine; Rh(I)-phosphine 22 in ethanol T=20°C; P=41371.8 Torr; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Takahashi, Hisashi; Achiwa, Kazuo
Chemistry Letters, 1989 , p. 305 - 308
反应条件
hydrogen; triethylamine; Rh(I)-phosphine 22 in ethanol T=20°C; P=41371.8 Torr; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Takahashi, Hisashi; Achiwa, Kazuo
Chemistry Letters, 1989 , p. 305 - 308
反应条件
lt;(R,R)-P,P'-lt;N-benzoylpyrrolidin-3,4-diylgt;bis(diphenylphosphan)gt;-1,5-cyclooctadienrhodium-tetrafluoroborate; hydrogen
参考文献
MacNeil, Patricia A.; Roberts, Nicholas K.; Bosnich, B.
Journal of the American Chemical Society, 1981 , vol. 103, # 9 p. 2273 - 2280
反应条件
1: 79 percent / 3 N HCl / 8 h / 80 °C 2: 78 percent / Zn(Hg), 3 N HCl / toluene / 8 h / 100 °C View Scheme
参考文献
Wong; Xu; Chang; Lee
Synthesis, 1992 , # 8 p. 793 - 797
反应条件
hydrogenchloride
T=100°C; 0.5 h;
参考文献
Wong; Xu; Chang; Lee
Synthesis, 1992 , # 8 p. 793 - 797
反应条件
potassium hydroxide
T=0°C; 5 h;
参考文献
Stafforst, Thorsten; Diederichsen, Ulf
European Journal of Organic Chemistry, 2007 , # 6 p. 899 - 911
反应条件
1: 90 percent / NaOAc / 5 h / 120 °C
2: 90 percent / 0.2 N HCl / 0.5 h / 100 °C
View Scheme
参考文献
Wong; Xu; Chang; Lee
Synthesis, 1992 , # 8 p. 793 - 797
