3',5'-二-O-(叔-丁基二甲基硅烷基)-2’-脱氧尿苷合成路线 (共 7 条)
反应条件
copper(II) sulfate in xylene Heating;
参考文献
Nucleosides, Nucleotides and Nucleic Acids, , vol. 27, # 8 p. 931 - 948
反应条件
K 10 clay in methanol; water T=75°C; 12 h;
参考文献
Asakura, Jun-Ichi; Robins, Morris J.; Asaka, Yukihiro; Kirn, Tong Hei
Journal of Organic Chemistry, 1996 , vol. 61, # 25 p. 9026 - 9027
反应条件
copper(II) sulfate in xylene Heating;
参考文献
Nucleosides, Nucleotides and Nucleic Acids, , vol. 27, # 8 p. 931 - 948
反应条件
palladium diacetate; acetic acid T=100°C; 5 h;
参考文献
Lee, Hyun Seung; Kim, Se Hee; Kim, Jae Nyoung
Bulletin of the Korean Chemical Society, 2010 , vol. 31, # 1 p. 238 - 241
反应条件
copper(II) sulfate in xylene
Heating;
参考文献
Cabral, Nadia L. D.; Thiessen, Luciano Hoeltgebaum; Doboszewski, Bogdan
Nucleosides, Nucleotides and Nucleic Acids, 2008 , vol. 27, # 8 p. 931 - 948
反应条件
N,N,N',N,-tetramethylethylenediamine; sec.-butyllithium in tetrahydrofuran
T=-78°C; Yield given. Yields of byproduct given;
参考文献
Armstrong, Robert W.; Gupta, Saaket; Whelihan, Fayelle
Tetrahedron Letters, 1989 , vol. 30, # 16 p. 2057 - 2060
反应条件
1: 73 percent / NaH / tetrahydrofuran
2: 97 percent / K2CO3 / aq. ethanol / 3 h / 25 °C
3: AcOH / tetrahydrofuran; H2O
4: 95 percent / conc. NH4OH / 0.5 h / 25 °C
View Scheme
参考文献
Coleman; Siedlecki
Tetrahedron Letters, 1991 , vol. 32, # 26 p. 3033 - 3034