1,2,3,4-四-O-乙酰基-Alpha-L-岩藻吡喃糖苷合成路线 （共 4 条）
反应条件
4 A molecular sieve; boron trifluoride diethyl etherate in dichloromethane T=20°C; 3 h;
参考文献
Ruttens, Bart; Kovac, Pavol
Synthesis, 2004 , # 15 p. 2505 - 2508
反应条件
1.1: HBr; AcOH / CH2Cl2 / 24 h / 0 - 20 °C 2.1: NaH / 1,2-dimethoxy-ethane / 0.5 h 2.2: 1,2-dimethoxy-ethane / 3 h / 20 °C View Scheme
参考文献
Ruttens, Bart; Kovac, Pavol
Synthesis, 2004 , # 15 p. 2505 - 2508
反应条件
1: zinc chloride / 120 °C / unter vermindertem Druck 2: sodium methylate; methanol View Scheme
参考文献
Levvy; McAllan
Biochemical Journal, 1961 , vol. 80, p. 433,434,435
Chem.Abstr., 1961 , # 27448
反应条件
1: 100 percent / aq. HBr, AcOH / 5 h / Ambient temperature
2: 67 percent / NaN3 / acetonitrile / 1.5 h / Heating; 1.) reflux, 90 min, 2.) RT, 17 h
View Scheme
参考文献
Abbott, Shaun D.; Gagnon, Lyne; Lagraoui, Mouna; Kadhim, Salam; Attardo, Giorgio; Zacharie, Boulos; Penney, Christopher L.
Journal of Medicinal Chemistry, 1998 , vol. 41, # 11 p. 1909 - 1926
