2-氧代-4-苯基丁酸乙酯合成路线 （共 50 条）
反应条件
1: 2-(phenyl)ethyl bromide With magnesium in tetrahydrofuran T=20°C; 1 h; Inert atmosphere; 2: oxalic acid diethyl ester in tetrahydrofuran T=-78°C; 2 h; Inert atmosphere;
参考文献
Angewandte Chemie - International Edition, , vol. 50, # 10 p. 2249 - 2252
反应条件
2,2,6,6-tetramethyl-1-piperidinyloxy, free radical; calcium methanolate in acetonitrile T=0 - 20°C;
参考文献
Synthetic Communications, , vol. 42, # 23 p. 3493 - 3503
反应条件
hydrogenchloride; sodium hypochlorite; tetrabutylammomium bromide in water T=0 - 40°C; Product distribution / selectivity;
参考文献
US2003/212293 A1, ;
Page/Page column 2 ;
反应条件
1,4-dihydro-1-propylpyridine-3-carboxamide; anhydrous magnesium perchlorate in acetonitrile Ambient temperature;
参考文献
Tetrahedron, , vol. 41, # 2 p. 467 - 472
反应条件
in tetrahydrofuran T=-10°C; 1 h;
参考文献
Synthetic Communications, , vol. 11, # 12 p. 943 - 946
反应条件
in diethyl ether T=-90°C; 1 h;
参考文献
Heterocycles, , vol. 49, # 1 p. 459 - 464
反应条件
1: 85 percent / HCO3(1-) 2: 41 percent / xylene 3: 82 percent / 1-n-propyl-1,4-dihydronicotinamide (PNAH, 4) / Mg(ClO4)2 / acetonitrile / Ambient temperature View Scheme
参考文献
Tetrahedron, , vol. 41, # 2 p. 467 - 472
反应条件
1: 41 percent / xylene 2: 82 percent / 1-n-propyl-1,4-dihydronicotinamide (PNAH, 4) / Mg(ClO4)2 / acetonitrile / Ambient temperature View Scheme
参考文献
Tetrahedron, , vol. 41, # 2 p. 467 - 472
反应条件
1: 78 percent Chromat. / NaOH / temp. <=10 deg C 2: 77 percent / hydrogen / Ni-Raney / ethanol; H2O / 4 h / Ambient temperature; other catalyst: Ni on Kieselguhr 3: 93 percent / SOCl2 / 10 h / Ambient temperature 4: 87 percent Chromat. / CrO3-pyridine / CH2Cl2 / 2.5 h / other reagents: K<CrO3Cl>, CrO3/Al2O3 View Scheme
参考文献
Synthetic Communications, , vol. 26, # 11 p. 2229 - 2233
