咪唑并[1,2-a]嘧啶-2-甲酸乙酯合成路线 （共 5 条）
反应条件
in ethanol T=75°C; 16 h;
参考文献
WO2006/71752 A1, ;
Page/Page column 83 ;
WO 2006/071752 A1
反应条件
1: bromine / dioxane; diethyl ether / 1 h 2: 1,2-dimethoxy-ethane / 48 h / Heating View Scheme
参考文献
Chemical and Pharmaceutical Bulletin, , vol. 40, # 5 p. 1170 - 1176
反应条件
in ethylene glycol dimethyl ether 48 h; Heating;
参考文献
Chemical and Pharmaceutical Bulletin, , vol. 40, # 5 p. 1170 - 1176
反应条件
N-bromosuccinmide in chloroform 12 h; Heating;
参考文献
European Journal of Medicinal Chemistry, , vol. 26, # 1 p. 13 - 18
反应条件
hydrazine in ethanol T=75°C; 16 h; Product distribution / selectivity;
参考文献
BRISTOL-MYERS SQUIBB COMPANY
Patent: WO2006/71752 A1, 2006 ;
Location in patent: Page/Page column 84 ;
WO 2006/071752 A1
