咪唑并[1,2-a]吡啶-2-羧酸合成路线 （共 3 条）
反应条件
1: With ethanol; water; sodium hydroxide T=60°C; 3 h; 2: With hydrogenchloride in water
参考文献
Bischoff, Alexander; Subramanya, Hosahalli; Sundaresan, Kumar; Sammeta, Srinivasa Raju; Vaka, Anil Kumar
Patent: US2010/160323 A1, 2010 ;
Location in patent: Page/Page column 31 ;
US 20100160323 A1
反应条件
1: 63 percent / tetrahydrofuran / 16 h / Heating 2: 45 percent / aq. KOH / ethanol / 1.5 h / 25 °C View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 46, # 18 p. 3914 - 3929
反应条件
hydrogen; platinum(IV) oxide in ethanol P=3000.3 Torr;
参考文献
ASTRAZENECA AB
Patent: WO2007/108750 A1, 2007 ;
Location in patent: Page/Page column 77 ;
WO 2007/108750 A1
