咪唑并[2,1-b]苯并噻唑-2-羧酸合成路线 （共 4 条）
反应条件
sodium hydroxide in ethanol 4 h; Heating;
参考文献
Ager; Barnes; Danswan; Hairsine; Kay; Kennewell; Matharu; Miller; Robson; Rowlands; Tully; Westwood
Journal of Medicinal Chemistry, 1988 , vol. 31, # 6 p. 1098 - 1115
反应条件
toluene-4-sulfonic acid in N,N-dimethyl-formamide T=125°C; P=3000.3 Torr; 0.166667 h; Automated synthesizer;
参考文献
Herath, Ananda; Dahl, Russell; Cosford, Nicholas D.P.
Organic Letters, 2010 , vol. 12, # 3 p. 412 - 415
反应条件
1: ethanol / 8 h / Heating 2: 2 N aq. NaOH / ethanol / 1 h / 60 °C View Scheme
参考文献
Farmaco, , vol. 51, # 7 p. 483 - 491
反应条件
1: tetrahydrofuran / 4 h 2: ethanol / 3 h / Heating 3: 77 percent / 1N NaOH / ethanol / 1 h / steam bath View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 31, # 6 p. 1220 - 1226
