potassium hydroxide; hydrazine hydrate in diethylene glycol T=200°C; Wolff-Kishner reduction; 1.5 h;

1: 96 percent / AcOH / 1 h / 110 °C 2: 80 percent / polyphosphoric acid / 1.5 h / 150 °C 3: 88 percent / hydrazine monohydrate; KOH / bis-(2-hydroxy-ethyl) ether / 1.5 h / 200 °C View Scheme

1: 80 percent / polyphosphoric acid / 1.5 h / 150 °C 2: 88 percent / hydrazine monohydrate; KOH / bis-(2-hydroxy-ethyl) ether / 1.5 h / 200 °C View Scheme

in N,N-dimethyl acetamide 1 h; Heating;