N-[3-(2-呋喃基)丙烯酰]-L-苯丙氨酰-甘氨酰-甘氨酸合成路线 (共 5 条)
反应条件
potassium hydroxide in methanol 5 h;
参考文献
Pozdnev, V. F.
J. Gen. Chem. USSR (Engl. Transl.), 1986 , vol. 56, # 3 p. 690 - 695,613 - 617
反应条件
1: 87 percent / triethylamine, N-hydroxybenzotriazole / dimethylformamide / 16 h 2: 93 percent / 4M HBr / acetic acid / 1 h 3: 82 percent / triethylamine / CH2Cl2 / 0.5 h 4: 76 percent / 1M KOH / methanol / 5 h View Scheme
参考文献
J. Gen. Chem. USSR (Engl. Transl.), , vol. 56, # 3 p. 690 - 695,613 - 617
反应条件
1: 82 percent / triethylamine / CH2Cl2 / 0.5 h 2: 76 percent / 1M KOH / methanol / 5 h View Scheme
参考文献
J. Gen. Chem. USSR (Engl. Transl.), , vol. 56, # 3 p. 690 - 695,613 - 617
反应条件
1: 93 percent / 4M HBr / acetic acid / 1 h 2: 82 percent / triethylamine / CH2Cl2 / 0.5 h 3: 76 percent / 1M KOH / methanol / 5 h View Scheme
参考文献
J. Gen. Chem. USSR (Engl. Transl.), , vol. 56, # 3 p. 690 - 695,613 - 617
反应条件
1: 92 percent / ditert-butyl pyrocarbonate, pyridine / ethyl acetate / 7 h / 15 - 25 °C 2: 82 percent / triethylamine / CH2Cl2 / 0.5 h 3: 76 percent / 1M KOH / methanol / 5 h View Scheme
参考文献
J. Gen. Chem. USSR (Engl. Transl.), , vol. 56, # 3 p. 690 - 695,613 - 617