2-氟-5-甲基苄醇; 2-氟-5-甲基苯甲醇合成路线 （共 3 条）
反应条件
(i) LiAlH4, Et2O, (ii) AcOEt, (iii) aq. NaOH; Multistep reaction;
参考文献
Hecht; Loy; Mazzarese; Hoffmann
Journal of medicinal chemistry, 1978 , vol. 21, # 1 p. 38 - 44
反应条件
1: (i) nBuLi, Et2O, (ii) /BRN= 1900390/
2: (i) LiAlH4, Et2O, (ii) AcOEt, (iii) aq. NaOH
View Scheme
参考文献
Hecht; Loy; Mazzarese; Hoffmann
Journal of medicinal chemistry, 1978 , vol. 21, # 1 p. 38 - 44
反应条件
boron tribromide
T=-45 - 20°C;
参考文献
ELI LILLY AND COMPANY
Patent: WO2007/15767 A1, 2007 ;
Location in patent: Page/Page column 47-48 ;
WO 2007/015767 A1
