1: sulfuric acid / 6 h / |Reflux 2: hydrazine hydrate / ethanol / 6 h / |Reflux 3: ethanol / 1 h / |Reflux View Scheme
参考文献
Abuo-Rahma, Gamal El-Din A.A.; Abdel-Aziz, Mohamed; Beshr, Eman A.M.; Ali, Taha F.S.
European Journal of Medicinal Chemistry, 2014 , vol. 71, p. 185 - 198
1: 2-amino-benzenethiol With 4-methoxytrityl resin chloride; N-ethyl-N,N-diisopropylamine in dichloromethane T=20°C; 2: benzoic acid With diisopropyl-carbodiimide in N,N-dimethyl-formamide T=20°C; 3 h; 3: With triethylsilane; trifluoroacetic acid in dichloromethane Title compound not separated from byproducts;