1: benzoic acid With borane-THF in tetrahydrofuran 2: With thionyl chloride Heating / reflux; 3: mercapto acetic acid ethylester With lithium hydroxide; water; sodium hydride more than 3 stages;
参考文献
ELAN PHARMACEUTICALS, INC.
Patent: WO2005/87714 A2, 2005 ;
Location in patent: Page/Page column 193 ;
WO 2005/087714 A2