Garcia-Munoz, Angel-Humberto; Tomas-Gamasa, Maria; Perez-Aguilar, M. Carmen; Cuevas-Yanez, Erick; Valdes, Carlos
European Journal of Organic Chemistry, 2012 , # 21 p. 3925 - 3928
1-bromo-1,1-dimethylethane; sodium hydrogencarbonate
T=25 - 30°C; 24 h; the similar reactions with a series of carboxylic acids and N-protected amino-acids; no desired products with other t-BuHal (Hal=Cl,I); other weak base (Et3N) is suitable; Mechanism;
参考文献
Dossena, Arnaldo; Marchelli, Rosangela; Casnati, Guiseppe
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1981 , p. 2737 - 2739
bromine; triethylamine
the same intermediates and product with t-BuOCl; Product distributionMechanism;
参考文献
Dossena, Arnaldo; Marchelli, Rosangela; Casnati, Guiseppe
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1981 , p. 2737 - 2739