2-甲氧基苯并环庚-5-酮合成路线 （共 42 条）
反应条件
1: 23 g / hydrogen / 10percent Pd-C / ethanol / 760 Torr / Ambient temperature 2: PCl5 / benzene / 0.5 h / Heating 3: SnCl4 / benzene / 24 h / Ambient temperature View Scheme
参考文献
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, , vol. 20, # 2 p. 140 - 143
反应条件
1.1: potassium tert-butylate / tetrahydrofuran / 1 h / 20 °C / Inert atmosphere 1.2: 12 h / 20 °C 2.1: hydrogen / palladium 10 on activated carbon / ethanol / 12 h 3.1: methanesulfonic acid; phosphorous pentoxide / 12 h / Inert atmosphere View Scheme
反应条件
1: hydrogen / palladium 10 on activated carbon / ethanol / 12 h 2: methanesulfonic acid; phosphorous pentoxide / 12 h / Inert atmosphere View Scheme
反应条件
barium permanganate in acetonitrile 2 h; Heating;
参考文献
Tetrahedron, , vol. 46, # 19 p. 6869 - 6878
反应条件
1: 1.) t-BuOK, 2.) aq. KOH / 1.) t-BuOH, 4 h, 2.) reflux, 12 h 2: 23 g / hydrogen / 10percent Pd-C / ethanol / 760 Torr / Ambient temperature 3: PCl5 / benzene / 0.5 h / Heating 4: SnCl4 / benzene / 24 h / Ambient temperature View Scheme
参考文献
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, , vol. 20, # 2 p. 140 - 143
反应条件
1.1: hydrogen / palladium 10 on activated carbon / tetrahydrofuran / 2 h / 20 °C / 2585.81 Torr 2.1: water; lithium hydroxide hydrate / tetrahydrofuran; methanol / 15 h / -5 - 20 °C 2.2: pH 2 - 3 3.1: PPA / chlorobenzene / 15 h / 80 °C View Scheme
反应条件
sulfuric acid; sodium iodide in tetrahydrofuran; water 24 h; Ambient temperature;
参考文献
Tetrahedron Letters, , vol. 21, p. 3195 - 3198
反应条件
1: 44 percent / red P, resublimed iodine / 5 h / 145 - 150 °C 2: 1.9 g / dilithium tetrachlorocuprate / tetrahydrofuran / 2 h / 0 °C 4: 89 percent / BuLi / tetrahydrofuran / 0.25 h / 0 °C 5: 59 percent / AgOTf / CH2Cl2 / 17 h / Ambient temperature View Scheme
参考文献
Tetrahedron, , vol. 43, # 8 p. 1847 - 1856
反应条件
1: 90 percent / LAH / tetrahydrofuran / 5 h / Heating 2: 44 percent / red P, resublimed iodine / 5 h / 145 - 150 °C 3: 1.9 g / dilithium tetrachlorocuprate / tetrahydrofuran / 2 h / 0 °C 5: 89 percent / BuLi / tetrahydrofuran / 0.25 h / 0 °C 6: 59 percent / AgOTf / CH2Cl2 / 17 h / Ambient temperature View Scheme
参考文献
Tetrahedron, , vol. 43, # 8 p. 1847 - 1856
反应条件
1: 1.9 g / dilithium tetrachlorocuprate / tetrahydrofuran / 2 h / 0 °C 3: 89 percent / BuLi / tetrahydrofuran / 0.25 h / 0 °C 4: 59 percent / AgOTf / CH2Cl2 / 17 h / Ambient temperature View Scheme
参考文献
Tetrahedron, , vol. 43, # 8 p. 1847 - 1856
