2-甲氧基羰氨基-3H-苯并咪唑-5-羧酸合成路线 （共 4 条）
反应条件
thionyl chloride in benzene 4 h; Heating;
参考文献
The Procter and Gamble Company
Patent: US6482843 B1, 2002 ;
反应条件
1: H2 / 10percent Pd-C/ Raney nickel / methanol / 6 h / 2280 Torr
2: 60 percent / ethanol / 5 h / Heating
View Scheme
参考文献
Naim, S. Shawkat; Singh, Sudhir K.; Sharma, Satyavan; Gupta, Suman; Fatma, N.; et al.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1988 , vol. 27, # 1-12 p. 1106 - 1109
反应条件
in ethanol
5 h; Heating;
参考文献
Naim, S. Shawkat; Singh, Sudhir K.; Sharma, Satyavan; Gupta, Suman; Fatma, N.; et al.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1988 , vol. 27, # 1-12 p. 1106 - 1109
反应条件
sodium hydroxide
1.) 10-15 deg C, 2.) 95 deg C, 2 h; Yield given. Multistep reaction;
参考文献
Ram; Wise; Wotring; McCall; Townsend
Journal of Medicinal Chemistry, 1992 , vol. 35, # 3 p. 539 - 547
