4-(1H-苯并咪唑-2-基)苯酚合成路线 （共 23 条）
参考文献
Profft et al.
Journal fuer Praktische Chemie (Leipzig), 1954 , vol. <4>1, p. 110,127
反应条件
1: 4-amino-phenol With hydrogenchloride; sodium nitrite in water
Cooling;
2: 1H-benzo[d]imidazole With sodium acetate in water
T=20°C; 51 h; Cooling;
参考文献
Sharma, Deepika; Narasimhan, Balasubramanian; Kumar, Pradeep; Jalbout, Abraham
European Journal of Medicinal Chemistry, 2009 , vol. 44, # 3 p. 1119 - 1127
反应条件
1: methanol / 1.5 h / 0 - 20 °C
2: benzofuroxan / methanol; acetonitrile / 2 h / 50 °C
View Scheme
参考文献
Patzold; Zeuner; Heyer; Niclas
Synthetic Communications, 1992 , vol. 22, # 2 p. 281 - 288
反应条件
aminosulfonic acid in ethanol
T=20°C; 4 h; Title compound not separated from byproducts;
参考文献
Chakrabarty, Manas; Karmakar, Sulakshana; Mukherji, Ajanta; Arima, Shiho; Harigaya, Yoshihiro
Heterocycles, 2006 , vol. 68, # 5 p. 967 - 974
反应条件
1: methanol / 1.5 h / 0 - 20 °C
2: benzofuroxan / methanol; acetonitrile / 2 h / 50 °C
View Scheme
参考文献
Patzold; Zeuner; Heyer; Niclas
Synthetic Communications, 1992 , vol. 22, # 2 p. 281 - 288
反应条件
in ethanol
3 h; Heating;
参考文献
Latif, N.; Mishriky, N.; Assad, F. M.; Meguid, S. Abdel
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1982 , vol. 21, # 9 p. 872 - 874
参考文献
Bahadur; Saxena; Pandey
Journal of the Indian Chemical Society, 1981 , vol. 58, # 10 p. 1018 - 1020
反应条件
hydrogenchloride
T=200°C;
参考文献
Profft et al.
Journal fuer Praktische Chemie (Leipzig), 1954 , vol. <4>1, p. 110,127
反应条件
1: 2.) H2O / 1.)Et2O, room temp., 1-2 h, 2) 50-60 deg C, 4 h
2: butan-1-ol / 2 h / Heating
View Scheme
参考文献
Latif, Nazih; Assaad, Fahmy M.; Hosni, Hanaa
Liebigs Annalen der Chemie, 1987 , p. 495 - 498
反应条件
1: pyridine
2: aqueous HCl / 200 °C
View Scheme
参考文献
Profft et al.
Journal fuer Praktische Chemie (Leipzig), 1954 , vol. <4>1, p. 110,127
