4-氯-1-(4-甲氧基苯基)-1H-吡唑并[3,4-d]嘧啶合成路线 （共 13 条）
反应条件
1: N,N-dimethyl-formamide / 1 h / 20 °C / |Inert atmosphere
2: triethylamine / acetonitrile / 24 h / 65 °C / |Inert atmosphere
View Scheme
参考文献
Morrill, Christie; Babu, Suresh; Almstead, Neilg.; Moon, Young-Choon
Synthesis (Germany), 2013 , vol. 45, # 13 art. no. SS-2013-C0248-OP, p. 1791 - 1806
反应条件
in acetonitrile
T=200°C; 0.0833333 h; Microwave irradiation; TimeConcentration;
参考文献
Morrill, Christie; Babu, Suresh; Almstead, Neilg.; Moon, Young-Choon
Synthesis (Germany), 2013 , vol. 45, # 13 art. no. SS-2013-C0248-OP, p. 1791 - 1806
反应条件
1: H2O / 24 h / Heating
2: POCl3; DMF / 4 h / Heating
View Scheme
参考文献
Peat, Andrew J.; Boucheron, Joyce A.; Dickerson, Scott H.; Garrido, Dulce; Mills, Wendy; Peckham, Jennifer; Preugschat, Frank; Smalley, Terrence; Schweiker, Stephanie L.; Wilson, Jayme R.; Wang, Tony Y.; Zhou, Huiqiang Q.; Thomson, Stephen A.
Bioorganic and Medicinal Chemistry Letters, 2004 , vol. 14, # 9 p. 2121 - 2125
