4-(吡咯烷-1-甲基)苯甲醛合成路线 （共 4 条）
反应条件
manganese(IV) oxide in 1,4-dioxane T=80°C; 1 h;
参考文献
SIGMA-TAU Industrie Farmaceutiche Riunite S.p.A.; GEMMA, Sandra
Patent: WO2007/104695 A1, 2007 ;
Location in patent: Page/Page column 27; 29 ;
反应条件
1: With sodium tris(acetoxy)borohydride; acetic acid; sodium sulfate in dichloromethane 72 h; 2: With potassium carbonate in dichloro difluoro methane 3: With hydrogenchloride; water; potassium carbonate more than 3 stages;
参考文献
EP1593667 A1, ;
Page/Page column 44-45 ;
EP 1593667 A1
反应条件
lithium aluminium tetrahydride in tetrahydrofuran; pentane T=20°C; 2 h;
参考文献
Sheng, Rong; Xu, Yu; Hu, Chunqi; Zhang, Jing; Lin, Xiao; Li, Jingya; Yang, Bo; He, Qiaojun; Hu, Yongzhou
European Journal of Medicinal Chemistry, 2009 , vol. 44, # 1 p. 7 - 17
反应条件
1: K2CO3; 18-crown-6 / acetone / Heating 2: LiAlH4 / tetrahydrofuran 3: MnO2 / dioxane / Heating View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 16, # 20 p. 5384 - 5388
