1,2,4,5-四氟-3,6-(三氟甲基)苯合成路线 （共 16 条）
反应条件
copper; zinc in water; N,N-dimethyl-formamide
T=70°C; 20 h; copper absence;
参考文献
Krasnov, Vyacheslav I.; Platonov, Vyacheslav E.; Beregovaya, Irina V.; Shchegoleva, Lyudmila N.
Tetrahedron, 1997 , vol. 53, # 5 p. 1797 - 1812
反应条件
copper; zinc in water; N,N-dimethyl-formamide
T=70°C; 10 h; other perfluoroxylenes, perfluoro-p-cymene, copper absence, water absence, other reaction time, other temperature; Product distributionMechanism;
参考文献
Krasnov, Vyacheslav I.; Platonov, Vyacheslav E.; Beregovaya, Irina V.; Shchegoleva, Lyudmila N.
Tetrahedron, 1997 , vol. 53, # 5 p. 1797 - 1812
反应条件
1: LiAlH4 / methanol
2: H2SO4 / 165 °C
View Scheme
参考文献
Aroskar,E.V. et al.
Journal of the Chemical Society, 1964 , p. 2975 - 2981
反应条件
1: 1.) SbF5, SiO2, 2.) H2O / 1.) 130 deg C, 3.5 h
2: SOCl2 / dimethylformamide / 3 h / 80 - 110 °C
3: KF / 16 h / 200 °C
View Scheme
参考文献
Karpov, V. M.; Panteleev, I. V.; Platonov, V. E.
Journal of Organic Chemistry USSR (English Translation), 1991 , vol. 27, p. 1932 - 1938
Zhurnal Organicheskoi Khimii, 1991 , vol. 27, p. 2183 - 2191
反应条件
SbF5; trifluoroacetic acid
T=50°C; 11 h;
参考文献
Zonov, Yaroslav V.; Karpov, Victor M.; Platonov, Vyacheslav E.
Journal of Fluorine Chemistry, 2007 , vol. 128, # 9 p. 1058 - 1064
反应条件
water; SbF5; silica gel
T=75°C; 4 h; also in the absence of SiO2; other temp. and time; multistep 1.) 75 deg C, 4 h; Product distribution;
参考文献
Karpov, V. M.; Panteleev, I. V.; Platonov, V. E.
Journal of Organic Chemistry USSR (English Translation), 1991 , vol. 27, p. 1932 - 1938
Zhurnal Organicheskoi Khimii, 1991 , vol. 27, p. 2183 - 2191
