1: With borane dimethyl sulfide in tetrahydrofuran T=0 - 70°C; 0.5 h; 2: With hydrogenchloride in tetrahydrofuran; water T=70°C; 1 h;

1: With acetic acid 0.333333 h; active carbon; 2: With hydrogen; palladium 10 on activated carbon in acetic acid

1.1: triethylamine; pivaloyl chloride; lithium chloride / tetrahydrofuran / -20 °C / Inert atmosphere 2.1: lithium hexamethyldisilazane / tetrahydrofuran / -40 °C / Inert atmosphere 3.1: water; lithium hydroxide hydrate; dihydrogen peroxide / tetrahydrofuran / 0 °C / Inert atmosphere 3.2: pH 1 4.1: triethylamine; diphenyl phosphoryl azide / toluene / 0.5 h / 80 °C 4.2: 3 h / Reflux 5.1: formic acid / 3 h / 50 °C / Inert atmosphere 6.1: 1,1'-carbonyldiimidazole / tetrahydrofuran / 0.17 h / 0 °C 6.2: 16 h / Inert atmosphere; Reflux 7.1: hydrogen / palladium-on-charcoal / water; tetrahydrofuran / 20 °C / 760.05 Torr View Scheme