4-(3-氯喹喔啉-2-基)哌嗪-1-羧酸叔丁酯合成路线 （共 3 条）
反应条件
triethylamine in dichloromethane
T=0 - 20°C;
参考文献
BIOVITRUM AB
Patent: WO2004/9586 A1, 2004 ;
Location in patent: Page 51 ;
WO 2004/009586 A1
反应条件
N-ethyl-N,N-diisopropylamine in 1,4-dioxane
T=80°C; 18 h;
参考文献
ENVOY THERAPEUTICS, INC.; HITCHCOCK, Stephen; MONENSCHEIN, Holger; REICHARD, Holly; SUN, Huikai; KIKUCHI, Shota; MACKLIN, Todd; HOPKINS, Maria
Patent: WO2014/28479 A1, 2014 ;
Location in patent: Paragraph 0155-0158 ;
反应条件
sodium hydroxide in water; dimethyl sulfoxide
T=100°C; 1 h;
参考文献
BIOVITRUM AB
Patent: WO2004/9586 A1, 2004 ;
Location in patent: Page 51 ;
WO 2004/009586 A1
