1,1-dimethylethylmagnesium chloride in diethyl ether T=0 - 20°C; 3 h;

1.1: 97 percent / methanol / 20 °C 2.1: TMSCl / tetrahydrofuran / 0.42 h 2.2: 86 percent / tetrahydrofuran / 3 h / 25 °C 3.1: 65 percent / t-BuMgCl / diethyl ether / 3 h / 0 - 20 °C View Scheme

1.1: TMSCl / tetrahydrofuran / 0.42 h 1.2: 86 percent / tetrahydrofuran / 3 h / 25 °C 2.1: 65 percent / t-BuMgCl / diethyl ether / 3 h / 0 - 20 °C View Scheme