hydrogen; Raney Nickel in methanol T=20°C; P=1500.15 Torr; 12 h;

1: hexane / 1.75 h / Reflux 2: hydrogenchloride / water; methanol / 4 h / 0 - 20 °C 3: pyridine; trichlorophosphate / toluene / 1 h / Reflux 4: methanesulfonic acid; dl-methionine / 16 h 5: hydrogen / Raney Nickel / methanol / 12 h / 20 °C / 1500.15 Torr View Scheme

1: hydrogenchloride / water; methanol / 4 h / 0 - 20 °C 2: pyridine; trichlorophosphate / toluene / 1 h / Reflux 3: methanesulfonic acid; dl-methionine / 16 h 4: hydrogen / Raney Nickel / methanol / 12 h / 20 °C / 1500.15 Torr View Scheme

1: pyridine; trichlorophosphate / toluene / 1 h / Reflux 2: methanesulfonic acid; dl-methionine / 16 h 3: hydrogen / Raney Nickel / methanol / 12 h / 20 °C / 1500.15 Torr View Scheme

1: methanesulfonic acid; dl-methionine / 16 h 2: hydrogen / Raney Nickel / methanol / 12 h / 20 °C / 1500.15 Torr View Scheme