反应条件
1: 1,2,3,4-tetrahydroquinolin-2-one With lithium diisopropyl amide in tetrahydrofuran
T=-78 - 20°C; 1.5 h;
2: 3-chloropropyl halide in tetrahydrofuran
T=-78 - 20°C; 1.5 h;
参考文献
Lee, Byoung Se; Chu, Soyoung; Lee, Kyo Chul; Lee, Bon-Su; Chi, Dae Yoon; Choe, Yearn Seong; Kim, Sang Eun; Song, Yun Seon; Jin, Changbae
Bioorganic and Medicinal Chemistry, 2003 , vol. 11, # 23 p. 4949 - 4958