3-[苯基-(甲苯-4-磺酰基)-氨基]-丙酸合成路线 （共 14 条）
反应条件
1: 97 percent / pyridine / 1) cooling, 15 min, 2) reflux, 30 min
2: 92 percent / 10 percent KOH / methanol; H2O / 4 h / Ambient temperature
View Scheme
参考文献
Kelkar, Prabhakar M.; Sangwan, Naresh K.; Rastogi, Shri Nivas; Anand, Nitya
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1980 , vol. 19, # 4 p. 297 - 300
参考文献
Clemo; Perkin
Journal of the Chemical Society, 1924 , vol. 125, p. 1618
反应条件
1: 1.) PCl5, 2.) AlCl3 / 1.) benzene, from 5 deg C to 23 deg C, 30 min, 2.) benzene 15-20 deg C, 3.5 h
2: 83 percent / gl. AcOH, aq. HCl / 3.5 h / Heating
3: conc. HCl / propan-2-ol / 17 h / Heating
View Scheme
参考文献
Werbel, L. M.; Kesten, S. J.; Turner, W. R.
European Journal of Medicinal Chemistry, 1993 , vol. 28, # 11 p. 837 - 852
反应条件
1: PCl5
2: 86 percent / AlCl3 / or SnCl4
3: 94 percent / NaOCH3 / methanol / 4 h / Ambient temperature
4: 91 percent / NH2NH2*H2O / acetic acid / 8 h / Heating
View Scheme
参考文献
Kelkar, Prabhakar M.; Sangwan, Naresh K.; Rastogi, Shri Nivas; Anand, Nitya
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1980 , vol. 19, # 4 p. 297 - 300
