1: With trimethylsilyl bromide in dichloromethane T=0°C; 0.5 h; Inert atmosphere; 2: With water; sodium hydrogencarbonate in dichloromethane Inert atmosphere;

lithium in N-methyl-acetamide

1.1: 4-(N,N-dimethlyamino)pyridine; N-ethyl-N,N-diisopropylamine / dichloromethane / 0 - 20 °C / Inert atmosphere 2.1: n-butyllithium; N,N,N',N,-tetramethylethylenediamine / diethyl ether; hexane / 5 h / 0 °C / Inert atmosphere 2.2: 0 °C / Inert atmosphere 3.1: trimethylsilyl bromide / dichloromethane / 0.5 h / 0 °C / Inert atmosphere 3.2: Inert atmosphere View Scheme

1.1: n-butyllithium; N,N,N',N,-tetramethylethylenediamine / diethyl ether; hexane / 5 h / 0 °C / Inert atmosphere 1.2: 0 °C / Inert atmosphere 2.1: trimethylsilyl bromide / dichloromethane / 0.5 h / 0 °C / Inert atmosphere 2.2: Inert atmosphere View Scheme