阿糖腺苷 2',3'-二乙酸酯合成路线 （共 3 条）
反应条件
Candida antarctica B lipase
T=30°C; pH=7; 24 h; aq. phosphate bufferEnzymatic reaction; regioselective reaction;
参考文献
Sabaini, Maria B.; Zinni, Maria A.; Mohorcic, Martina; Friedrich, Jozefa; Iribarren, Adolfo M.; Iglesias, Luis E.
Journal of Molecular Catalysis B: Enzymatic, 2010 , vol. 62, # 3-4 p. 225 - 229
反应条件
1: pyridine / 24 h / Ambient temperature
2: pyridine / 7 h / 3 °C
3: TBAF/CH3CO2H
View Scheme
参考文献
Wnuk, Stanislaw F.; Yuan, Chong-Sheng; Borchardt, Ronald T.; Balzarini, Jan; De Clercq, Erik; Robins, Morris J.
Journal of Medicinal Chemistry, 1997 , vol. 40, # 11 p. 1608 - 1618
反应条件
1: pyridine / 7 h / 3 °C
2: TBAF/CH3CO2H
View Scheme
参考文献
Wnuk, Stanislaw F.; Yuan, Chong-Sheng; Borchardt, Ronald T.; Balzarini, Jan; De Clercq, Erik; Robins, Morris J.
Journal of Medicinal Chemistry, 1997 , vol. 40, # 11 p. 1608 - 1618
