2,3,5,6-四氟苯甲酸合成路线 （共 27 条）
反应条件
zinc in ammonium hydroxide 5 h; Ambient temperature;
参考文献
Laev, Sergey S.; Shteingarts, Vitalii D.
Journal of Fluorine Chemistry, 1999 , vol. 96, # 2 p. 175 - 185
反应条件
1: With CsOH; [Cu(IPr)(OH)] in tetrahydrofuran T=65°C; 8 h; Inert atmosphere; 2: With hydrogenchloride in water Inert atmosphere;
参考文献
Boogaerts, Ine I. F.; Fortman, George C.; Furst, Marc R. L.; Cazin, Catherine S. J.; Nolan, Steven P.
Angewandte Chemie - International Edition, 2010 , vol. 49, # 46 p. 8674 - 8677
反应条件
sulfuric acid in water
反应条件
4-(N,N-dimethlyamino)pyridine; C21H27AuN2 in dichloromethane T=40°C; 12 h; Inert atmosphere;
参考文献
Lv, Hongbin; Zhan, Jin-Hui; Cai, Yuan-Bo; Yu, Yi; Wang, Bingwu; Zhang, Jun-Long
Journal of the American Chemical Society, 2012 , vol. 134, # 39 p. 16216 - 16227,12
反应条件
1: 1,2,4,5-tetrafluorobenzene With n-butyllithium in tetrahydrofuran; hexane T=-75 - -60°C; 1 h; Inert atmosphere; 2: carbon dioxide in tetrahydrofuran; hexane T=-70 - 20°C; 1 h; Inert atmosphere; 3: With hydrogenchloride; water in tetrahydrofuran; hexane T=0°C;
参考文献
Orthaber, Andreas; Seidel, Christiane; Belaj, Ferdinand; Albering, Joerg H.; Pietschnig, Rudolf; Ruschewitz, Uwe
Inorganic Chemistry, 2010 , vol. 49, # 20 p. 9350 - 9357
反应条件
ammonium hydroxide; zinc T=20°C; Dehalogenation; 4 h;
参考文献
Laev, Sergey S.; Shteingarts, Vitalii D.
Journal of Fluorine Chemistry, 1999 , vol. 96, # 2 p. 175 - 185
参考文献
Zeneca Limited
Patent: US5792887 A1, 1998 ;
反应条件
in tetrahydrofuran; hexane; water
反应条件
in perchloric acid Electrochem. Process; at -1.5 V;
参考文献
Gmelin Handbook: F: PerFHalOrg.7, 1, page 1 - 84
反应条件
in tetrahydrofuran; hexane; water
