2,3,5,6-四氟苯甲酸合成路线 （共 27 条）
反应条件
lithium aluminium tetrahydride; hydrogen bromide Multistep reaction;
参考文献
Thorson, Jon S.; Chapman, Eli; Murphy, Elizabeth C.; Schultz, Peter G.; Judice, J. Kevin
Journal of the American Chemical Society, 1995 , vol. 117, # 3 p. 1157 - 1158
反应条件
N,N,N',N'-tetra-methylnaphthalene-1,8-diamine in acetonitrile T=19.85°C; Activation energyKinetics; Further Variations:pH-valuesReaction partnersTemperatures;
参考文献
Journal of Physical Organic Chemistry, , vol. 14, # 10 p. 691 - 696
反应条件
sodium tetrahydroborate; sulfuryl dichloride; tetrabutylammomium bromide Yield given. Multistep reaction;
参考文献
Costello, Alan T.; Milner, David J.
Synthetic Communications, 1986 , vol. 16, # 10 p. 1173 - 1176
反应条件
thionyl chloride in benzene 5 h; Heating;
参考文献
Chazalette, Celine; Masereel, Bernard; Rolin, Stephanie; Thiry, Anne; Scozzafava, Andrea; Innocenti, Alessio; Supuran, Claudiu T.
Bioorganic and Medicinal Chemistry Letters, 2004 , vol. 14, # 23 p. 5781 - 5786
反应条件
thionyl chloride in methanol
参考文献
IMPERIAL CHEMICAL INDUSTRIES PLC
Patent: EP266947 B1, 1991 ;
反应条件
by lithiation, followed by react. with sulfur at -60°C;
参考文献
Tamborski, C.; Soloski, E. J.
Journal of Organic Chemistry, 1966 , vol. 31, p. 743 - 745
反应条件
ammonia; sodium
T=-45°C; Reduction; Hydrodefluorination; 0.25 h; Title compound not separated from byproducts;
参考文献
Konovalov, Valery V.; Laev, Sergey S.; Beregovaya, Irina V.; Shchegoleva, Lyudmila N.; Shteingarts, Vitalij D.; Tsvetkov, Yuri D.; Bilkis, Itzhak
Journal of Physical Chemistry A, 2000 , vol. 104, # 2 p. 352 - 361
