2',3',4',5',6'-五氟苯乙酮合成路线 （共 46 条）
反应条件
dimethylphenylsilane; bis(1,2-diphenylphosphino)benzene; potassium tert-butylate; copper(l) chloride in tetrahydrofuran 12 h; Inert atmosphereReflux; regioselective reaction;
参考文献
Lv, Hongbin; Cai, Yuan-Bo; Zhang, Jun-Long
Angewandte Chemie - International Edition, 2013 , vol. 52, # 11 p. 3203 - 3207
Angew. Chem., 2013 , vol. 125, # 11 p. 3285 - 3289,5
反应条件
ethanol; Titanium(IV) oxide T=32°C; 2 h; Inert atmosphereUV-irradiation;
参考文献
Kohtani, Shigeru; Yoshioka, Eito; Saito, Kenji; Kudo, Akihiko; Miyabe, Hideto
Catalysis Communications, 2010 , vol. 11, # 13 p. 1049 - 1053
反应条件
t-Bu-XantPhos; tBuXantphosAu(AuCl2); (Ph)2SiH2; acetic acid in 1,2-dichloro-ethane T=80°C; 24 h; Inert atmosphere;
参考文献
Zhan, Jin-Hui; Lv, Hongbin; Yu, Yi; Zhang, Jun-Long
Advanced Synthesis and Catalysis, 2012 , vol. 354, # 8 p. 1529 - 1541
反应条件
(S)-Noyori-reagent T=-115°C; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Brandt, Peter; Roth, Peter; Andersson, Pher G.
Journal of Organic Chemistry, 2004 , vol. 69, # 15 p. 4885 - 4890
反应条件
[ReOCl3((R)-1-[(Sp)-2-(dicyclohexyl)ferrocenyl]ethyldi[3,5-bis(trifluoromethyl)phenyl]phosphane)]; triethylamine in isopropyl alcohol T=80°C; 20 h; Inert atmosphereSchlenk technique;
参考文献
Mejia, Esteban; Aardoom, Raphael; Togni, Antonio
European Journal of Inorganic Chemistry, 2012 , # 31 p. 5021 - 5032,12
参考文献
James,J.H.; Peach,M.E.
Journal of Fluorine Chemistry, 1985 , vol. 27, p. 91
反应条件
4-(N,N-dimethlyamino)pyridine; C21H27AuN2 in dichloromethane T=40°C; 12 h; Inert atmosphere;
参考文献
Lv, Hongbin; Zhan, Jin-Hui; Cai, Yuan-Bo; Yu, Yi; Wang, Bingwu; Zhang, Jun-Long
Journal of the American Chemical Society, 2012 , vol. 134, # 39 p. 16216 - 16227,12
反应条件
sodium hydride; dimethyl sulfoxide T=35°C; 40 h;
参考文献
Joshi, Krishna C.; Pathak, Vijai N.; Grover, Vineeta
Journal of Fluorine Chemistry, 1980 , vol. 15, p. 245 - 252
反应条件
2.) P.P.A. 2.) 125-150 deg C; Multistep reaction;
参考文献
Joshi, Krishna C.; Pathak, Vijay N.; Gupta, Ragini
Journal of Fluorine Chemistry, 1988 , vol. 38, p. 153 - 162
反应条件
(S)-Noyori-reagent
T=-115°C; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Brandt, Peter; Roth, Peter; Andersson, Pher G.
Journal of Organic Chemistry, 2004 , vol. 69, # 15 p. 4885 - 4890
