2',3',4',5',6'-五氟苯乙酮合成路线 （共 46 条）
反应条件
1: 1.) LiH, 2.) aq. Cu(OAc)2 / 1) heating; 3) heating, DMSO, 20 min
2: 80 percent / AcOH, conc. HCl / 6 h / Heating
View Scheme
参考文献
Saloutin, V. I.; Skryabina, Z. E.; Bazyl', I. T.; Chupakhin, O. N.
Journal of Fluorine Chemistry, 1993 , vol. 65, # 1-2 p. 37 - 42
反应条件
1: 70 percent / selenium dioxide / dioxane; H2O / 6 h / Heating
2: ethanol; H2O / 0.17 h / Heating
3: potassium carbonate / ethanol; H2O / 8 h / Heating
View Scheme
参考文献
Joshi, Krishna C.; Dubey, Kalpana; Dandia, Anshu
Heterocycles, 1981 , vol. 16, # 9 p. 1545 - 1553
反应条件
hydridotetrakis(triphenylphosphine)rhodium (Ph3P)4RhH; cis-DPPEthylene in chlorobenzene
2 h; Inert atmosphereReflux;
参考文献
Arisawa, Mieko; Igarashi, Yui; Kobayashi, Haruki; Yamada, Toru; Bando, Kentaro; Ichikawa, Takuya; Yamaguchi, Masahiko
Tetrahedron, 2011 , vol. 67, # 40 p. 7846 - 7859
参考文献
James,J.H.; Peach,M.E.
Journal of Fluorine Chemistry, 1985 , vol. 27, p. 91
反应条件
hydridotetrakis(triphenylphosphine)rhodium (Ph3P)4RhH; tri-iso-propylsilane; bis(1,2-diphenylphosphino)benzene in tetrahydrofuran
6 h; RefluxInert atmosphere;
参考文献
Arisawa, Mieko; Ichikawa, Takuya; Yamaguchi, Masahiko
Tetrahedron Letters, 2013 , vol. 54, # 32 p. 4327 - 4329
反应条件
hydridotetrakis(triphenylphosphine)rhodium (Ph3P)4RhH; tri(n-butyl)silane; bis(2-methyl-2-propyl)tetrasulfide; bis(1,2-diphenylphosphino)benzene in N,N-dimethyl-formamide
T=80°C; 6 h;
参考文献
Arisawa, Mieko; Ichikawa, Takuya; Yamaguchi, Masahiko
Organic Letters, 2012 , vol. 14, # 20 p. 5318 - 5321
