1-(三氟乙酰基)-4-哌啶酮合成路线 (共 4 条)
反应条件
triethylamine in dichloromethane T=0 - 20°C; 2.16667 h;
参考文献
ACADIA PHARMACEUTICALS, INC.
Patent: WO2007/124136 A1, 2007 ;
Location in patent: Page/Page column 131 ;
WO 2007/124136 A1
反应条件
oxalyl dichloride; dimethyl sulfoxide; triethylamine in dichloromethane T=-78 - 20°C; Swern oxidation;
参考文献
Wessig, Pablo; Moellnitz, Kristian
Journal of Organic Chemistry, 2008 , vol. 73, # 12 p. 4452 - 4457
反应条件
trifluoroacetic anhydride in pyridine
反应条件
trifluoroacetic anhydride